Centennial College has been recognized as a culturally diverse post-secondary institution, almost 100 ethno-cultural groups are represented and 80 languages are spoken on campus. In 2016, it was ranked as one of Canada’s Top 10 Research Colleges. Its main research facilities are its Wearable, Interactive and Mobile Technologies Access Centre in Healthcare (WIMTACH]), established in 2015 through a $1.75 million federal grant and its aerospace innovation hub, under construction at the former de Havilland plant in west-end Toronto.

Centennial College offers full-time programs in more than 100 fields of study. These programs emphasize experiential learning with laboratory instruction, paid co-operative education opportunities, and industry and agency field placements. All Centennial programs are developed and kept current with the assistance of program advisory committees (PACs), made up of academic advisors and employer representatives. Their participation ensures the education and skills students receive at Centennial are up-to-date and relevant to the industry they are preparing to enter.

Centennial offers a variety of innovative degree programs. Five joint-degree programs in paramedicine, journalism, new media studies, environmental science & technology and applied microbiology are taught in conjunction with the University of Toronto Scarborough and the Bachelor of Science Nursing program is delivered jointly with Ryerson university Centennial was among the first colleges in Ontario to receive approval for applied-degree programs in computer and communication networking, and software systems: design, development and management.